Welcome to Crybabies with Sarah Thyre and Susan Orlean. A show about celebrating all the things that make us cry. Sarah and Susan’s Cry of the Week choices lead them to talk about how they know each other, The Tale of Despereaux, Lou Rawls’ “Pure Imagination,” The Bangles’ “Eternal Flame,” and immersing yourself in heart break. Then, they are joined by actor, screenwriter, director, comedian Christopher Guest to chat about what makes him cry, having to cry on cue in a film, and the forever evolving crying triggers in It’s A Wonderful Life. Finally, Sarah and Susan discuss Pixar’s Up as they go through some Twitter submitted crying cues.