subscribe

dalesd / Dan

There are no people in dalesd’s collective.

Huffduffed (600)

  1. Why Cholesterol Levels Have No Effect on Cardiovascular Disease (And Things to Think about Instead) | Nourish Balance Thrive

    April 16, 2018

    Dr. Malcolm Kendrick is a medical doctor, author, speaker, and sceptic living in Cheshire, England.  His evidence-based arguments refute the lipid hypothesis and other ideas related to chronic illness that has resulted in a pervasive culture of fear and misinformation.  His popular blog features an ongoing series of posts on the real causes of heart disease, pointing to endothelial damage as a causal factor and nitric oxide as vital for preserving health.

    Dr. Kendrick is with us to share not only what really causes cardiovascular disease, but the specific environmental and psychosocial factors that cause the most harm, and what we need to do to maintain good health. We also discuss unexpected side effects of common medications and supplements and the healing power of specific micronutrients.  If you enjoy this podcast, you can support Dr. Kendrick’s work by pre-ordering his latest book, A Statin Nation: Damaging Millions in a Brave New Post-Health World, available 7/12/18.

    Here’s the outline of this interview with Malcolm Kendrick:

    [00:01:05] Book: The Great Cholesterol Con: The Truth About What Really Causes Heart Disease and How to Avoid it, by Malcolm Kendrick.

    [00:01:07] Book: Doctoring Data: How to Sort Out Medical Advice from Medical Nonsense, by Malcolm Kendrick.

    [00:01:14] The International Network of Cholesterol Skeptics (THINCS).

    [00:01:46] Trail Runner Nation Podcast: Metabolic Flexibility with Christopher Kelly.

    [00:02:59] Highlights email series.

    [00:03:01] Podcast: The True Root Causes of Cardiovascular Disease, with Jeffry Gerber.

    [00:03:07] Blog series: What causes heart disease?

    [00:05:28] Study: Hayashi, Keiko, et al. "Laughter lowered the increase in postprandial blood glucose." Diabetes care 26.5 (2003): 1651-1652.

    [00:06:20] Stress hormones, sympathetic nervous system.

    [00:07:32] Graph: Lithuanian death rate; Study: Kristenson, Margareta, et al. "Increased psychosocial strain in Lithuanian versus Swedish men: the LiVicordia study." Psychosomatic Medicine 60.3 (1998): 277-282.

    [00:08:25] Paul Rosch, M.D, founder of the American Institute of Stress.

    [00:10:20] Endothelium, glycocalyx.

    [00:11:12] Nitric Oxide (NO).

    [00:11:37] Alfred Nobel, nitroglycerin (glyceryl trinitrate, or GTN), Viagra.

    [00:13:13] Study: Andersson, Daniel P., et al. "Association between treatment for erectile dysfunction and death or cardiovascular outcomes after myocardial infarction." Heart (2017): heartjnl-2016.

    [00:13:39] Sunlight as nitric oxide stimulant.

    [00:14:45] Vasculitis, Systemic lupus erythematosus (SLE), Rheumatoid arthritis, Sickle-cell disease.

    [00:17:05] Endothelial progenitor cells.

    [00:17:55] Carl von Rokitansky, Rudolf Virchow.

    [00:21:19] Endothelial damage required for arterial plaque.

    [00:21:52] Study: Law, M. R., and S. G. Thompson. "Low serum cholesterol and the risk of cancer: an analysis of the published prospective studies." Cancer causes & control 2.4 (1991): 253-261.

    [00:23:49] Study: Ravnskov, Uffe, et al. "Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review." BMJ open 6.6 (2016): e010401.

    [00:25:03] Statins increasing NO, studies: 1, 2, 3.

    [00:26:52] Study: Lanphear, Bruce P., et al. "Low-level lead exposure and mortality in US adults: a population-based cohort study." The Lancet Public Health (2018).

    [00:28:17] Corticosteroids.

    [00:30:25] Familial Hypercholesterolemia.

    [00:34:56] Study: Winnik, Stephan, et al. "Systemic VEGF inhibition accelerates experimental atherosclerosis and disrupts endothelial homeostasis–implications for cardiovascular safety." International journal of cardiology 168.3 (2013): 2453-2461.

    [00:36:29] QRISK survey for heart disease.

    [00:41:21] Inflammation as healing.

    [00:42:40] Study: Willis, G. C. "The reversibility of atherosclerosis." Canadian Medical Association Journal 77.2 (1957): 106.

    [00:44:36] Corticosteroids reduce inflammation, increase CVD risk, NSAIDs.

    [00:45:05] Study: Guilhem, Gaël, et al. "Effects of air-pulsed cryotherapy on neuromuscular recovery subsequent to exercise-induced muscle damage." The American journal of sports medicine 41.8 (2013): 1942-1951.

    [00:49:06] Lipoprotein A.

    [00:51:27] Vitamin C deficiency as possible cause of CVD.

    [00:53:01] Study: Lee, A. J., et al. "Plasma fibrinogen and coronary risk factors: the Scottish Heart Health Study." Journal of clinical epidemiology 43.9 (1990): 913-919.

    [00:55:27] Diabetes, triglycerides, sepsis, gingivitis as procoagulants.

    [00:58:39] Major endothelial offenders.

    [01:00:03] Study: Escolar, Esteban, et al. "The effect of an EDTA-based chelation regimen on patients with diabetes mellitus and prior myocardial infarction in the Trial to Assess Chelation Therapy (TACT)." Circulation: Cardiovascular Quality and Outcomes (2013): CIRCOUTCOMES-113.

    [01:01:03] Study: Douaud, Gwenaëlle, et al. "Preventing Alzheimer’s disease-related gray matter atrophy by B-vitamin treatment." Proceedings of the National Academy of Sciences 110.23 (2013): 9523-9528.

    [01:01:44] Study: Marik, Paul E., et al. "Hydrocortisone, vitamin C, and thiamine for the treatment of severe sepsis and septic shock: a retrospective before-after study." Chest 151.6 (2017): 1229-1238.

    [01:02:27] Allen Smith, dying of flu, recovered with Vitamin C.

    [01:03:13] sunlight, viagra, stress management, alcohol.

    [01:04:23] Blue zones, strong social relationships.

    [01:05:07] Lifestyle and environmental factors associated with lower life expectancy.

    [01:13:05] Statins.

    [01:15:49] Absolute risk vs. relative risk; side effect vs. adverse effect, adverse events.

    [01:21:07] Problems caused by statins.

    [01:21:29] CoQ10, ATP.

    [01:23:47] Placebo effect, nocebo effect.

    [01:24:40] Study: Gupta, Ajay, et al. "Adverse events associated with unblinded, but not with blinded, statin therapy in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid-Lowering Arm (ASCOT-LLA): a randomised double-blind placebo-controlled trial and its non-randomised non-blind extension phase." The Lancet 389.10088 (2017): 2473-2481.

    [01:25:45] Study: Cohen, Jerome D., et al. "Understanding Statin Use in America and Gaps in Patient Education (USAGE): an internet-based survey of 10,138 current and former statin users." Journal of clinical lipidology 6.3 (2012): 208-215.

    [01:26:32] PCSK9 inhibitors.

    [01:27:54] Study: Sabatine, Marc S., et al. "Evolocumab and clinical outcomes in patients with cardiovascular disease." New England Journal of Medicine 376.18 (2017): 1713-1722.

    [01:35:16] L-arginine, citrulline.

    [01:39:34] Study: Tunstall-Pedoe, Hugh. "Does dietary potassium lower blood pressure and protect against coronary heart disease and death? Findings from the Scottish Heart Health Study?." Seminars in nephrology. Vol. 19. No. 5. 1999.

    [01:40:40] Study: Graudal, Niels. "A radical sodium reduction policy is not supported by randomized controlled trials or observational studies: grading the evidence." American journal of hypertension 29.5 (2016): 543-548.

    [01:43:55] Groupthink, cognitive bias.

    [01:44:21] Michael Alderman, M.D.

    [01:44:48] Evolutionary Psychology.

    [01:45:58] Peer Review.

    [01:51:36] Study: Bronstein, Alvin C., et al. "2010 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 28th Annual Report." Clinical Toxicology 49.10 (2011): 910-941.

    [01:52:57] Book: A Statin Nation: Damaging Millions in a Brave New Post-Health World, by Malcolm Kendrick.  

    [01:57:37] drmalcolmkendrick.org.

    http://www.nourishbalancethrive.com/podcasts/nourish-balance-thrive/why-cholesterol-levels-have-no-effect-cardiovascul/

    —Huffduffed by dalesd

  2. DDAL00-02A The Darkwood Webs 2017-08-25

    Broadcasted live on Twitch — Watch live at https://www.twitch.tv/d20play

    ===
    Original video: https://www.youtube.com/watch?v=GNMQq04eoQQ
    Downloaded by http://huffduff-video.snarfed.org/ on Mon, 07 May 2018 23:57:44 GMT Available for 30 days after download

    download

    Tagged with gaming

    —Huffduffed by dalesd

  3. lobsterdust - Can’t Stop The Summer (Oliver Heldens x Lana Del Rey x ZHU)

    Original video: https://www.youtube.com/watch?v=MdllqDynkeA
    Downloaded by http://huffduff-video.snarfed.org/ on Mon, 07 May 2018 21:21:35 GMT Available for 30 days after download

    download

    Tagged with music

    —Huffduffed by dalesd

  4. DDAL00-02B The Weirding Vats 2018-03-30

    Broadcasted live on Twitch — Watch live at https://www.twitch.tv/d20play

    ===
    Original video: https://www.youtube.com/watch?v=qdzSfIAngA8
    Downloaded by http://huffduff-video.snarfed.org/ on Wed, 02 May 2018 12:40:51 GMT Available for 30 days after download

    download

    Tagged with gaming

    —Huffduffed by dalesd

  5. Adventure League DDAL05-16 - Parnast Under Siege Quest of The Week

    Despite the adventurers’ best efforts, more creatures joined under Bad Fruul’s banner. No longer content to simply attack caravans or isolated homesteads, the hill giant warlord descends upon Parnast at the head of a great force of humanoids. SEER warns the adventurers (directly now) in time to rally the town and prepare defenses, but a heroic effort is required to break the siege. — Watch live at https://www.twitch.tv/sykus29xp

    ===
    Original video: https://www.youtube.com/watch?v=XXdFcnHpty4
    Downloaded by http://huffduff-video.snarfed.org/ on Mon, 30 Apr 2018 15:47:56 GMT Available for 30 days after download

    download

    Tagged with gaming

    —Huffduffed by dalesd

  6. Kate Welch on Why D&D is so Memorable

    dndbeyond.com

    An official digital toolset for Dungeons & Dragons fifth edition.

    ===
    Original video: https://www.youtube.com/watch?time_continue=78&v=3wnE9eR1N7I
    Downloaded by http://huffduff-video.snarfed.org/ on Thu, 26 Apr 2018 20:13:26 GMT Available for 30 days after download

    download

    Tagged with gaming

    —Huffduffed by dalesd

  7. Aphex Twin and Taylor Swift – You Belong With Avril | Today Sounds Like

    http://annenoise.com/music/wp-content/uploads/2014/11/08-You-Belong-With-Avril.m4aWho would have thought that one of my favorite Aphex Twin songs and one of my favorite Taylor Swift songs would mash up into a flawless masterpiece?

    Mixed by David Rees, who is clearly a genius.

    http://annenoise.com/music/?p=833

    —Huffduffed by dalesd

  8. ALOCON:OtS: DDAL05-16 Parnast Under Siege

    ALOCON Of The Storm - kicks off with GrumpyOldDM running Parnast Under Siege (DDAL05-16)

    Despite the adventurers’ best efforts, more creatures joined under Bad Fruul’s banner.

    No longer content to simply attack caravans or isolated homesteads, the hill giant warlord descends upon Parnast at the head of a great force of humanoids.

    SEER warns the adventurers (directly now) in time to rally the town and prepare defenses, but a heroic effort is required to break the siege.

    A Four-Hour Adventure for 1st-4th Level Characters

    Blog ——— http://www.grumpyolddm.com Twitch ——— https://www.twitch.tv/grumpyolddm Twitter ——— https://twitter.com/GrumpyOldDM Facebook - https://www.facebook.com/GrumpyOldDM/ Roll20 ——— https://app.roll20.net/users/1486161

    ===
    Original video: https://www.youtube.com/watch?v=DjBKflhQntc
    Downloaded by http://huffduff-video.snarfed.org/ on Mon, 23 Apr 2018 14:07:21 GMT Available for 30 days after download

    download

    Tagged with gaming

    —Huffduffed by dalesd

  9. Red Hot Chili Peppers vs. The Ting Tings (Lobsterdust Mashup)

    Red Hot Chili Peppers - Give It Away Now The Ting Tings - Shut Up And Let Me Go

    ===
    Original video: https://www.youtube.com/watch?v=DSpNvF5IDz4&index=15&list=PL-b1L0xfoKkRAc0dbNfRs7igoHYnfqZ-q
    Downloaded by http://huffduff-video.snarfed.org/ on Sat, 21 Apr 2018 08:26:01 GMT Available for 30 days after download

    download

    Tagged with music

    —Huffduffed by dalesd

  10. DJ Lobsterdust - We Found A Good Beat

    Check out my Fitness/Indoor Cycling website at www.DennisMellonFitness.com

    ===
    Original video: https://www.youtube.com/watch?v=K1dPmCr8RDc&index=11&list=PL-b1L0xfoKkRAc0dbNfRs7igoHYnfqZ-q
    Downloaded by http://huffduff-video.snarfed.org/ on Sat, 21 Apr 2018 08:06:51 GMT Available for 30 days after download

    download

    Tagged with music

    —Huffduffed by dalesd

Page 1 of 60Older