69% higher risk of Alzheimer's for older COVID survivors
Older COVID-19 survivors,
69% higher risk of developing Alzheimer's disease,
within 1 year of infection
Medical records of 6,245,282
65 years and older
Medical visits but no previous diagnosis of Alzheimer's disease
February 2020 to May 2021
410,748 participants tested positive for COVID-19
5,834,534 did not test positive
COVID-19 survivors had a 69% higher risk of a new diagnosis of Alzheimer's disease within 1 year of infection than their uninfected peers
Hazard ratio 1.69; 95% (1.53 to 1.72)
Most at risk
Ages 85 and older, HR = 1.89
Women, HR = 1.82
Association of COVID-19 with New-Onset Alzheimer’s Disease
https://content.iospress.com/articles/journal-of-alzheimers-disease/jad220717
Journal of Alzheimer's Disease, vol. 89, no. 2, pp. 411-414, 2022
13th September 2022
Infectious etiology of Alzheimer’s disease, postulated for decades
So, is SARS-CoV-2 infection associated with increased risk for Alzheimer’s disease?
Retrospective cohort study
N = 6,245,282 older adults (age ≥65 years),
People with COVID-19 were at significantly increased risk for new diagnosis of Alzheimer’s disease
Within 360 days after the init…
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