Post covid Alzheimer’s

69% higher risk of Alzheimer's for older COVID survivors

Older COVID-19 survivors,

69% higher risk of developing Alzheimer's disease,

within 1 year of infection

Medical records of 6,245,282

65 years and older

Medical visits but no previous diagnosis of Alzheimer's disease

February 2020 to May 2021

410,748 participants tested positive for COVID-19

5,834,534 did not test positive

COVID-19 survivors had a 69% higher risk of a new diagnosis of Alzheimer's disease within 1 year of infection than their uninfected peers

Hazard ratio 1.69; 95% (1.53 to 1.72)

Most at risk

Ages 85 and older, HR = 1.89

Women, HR = 1.82

Association of COVID-19 with New-Onset Alzheimer’s Disease

Journal of Alzheimer's Disease, vol. 89, no. 2, pp. 411-414, 2022

13th September 2022

Infectious etiology of Alzheimer’s disease, postulated for decades

So, is SARS-CoV-2 infection associated with increased risk for Alzheimer’s disease?

Retrospective cohort study

N = 6,245,282 older adults (age ≥65 years),

People with COVID-19 were at significantly increased risk for new diagnosis of Alzheimer’s disease

Within 360 days after the init…

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