Episode 53 of the Brain Science Podcast is a discussion of Did My Neurons Make Me Do It?: Philosophical and Neurobiological Perspectives on Moral Responsibility and Free Will by Nancey Murphy and Warren S. Brown. This book challenges the widespread fear that neuroscience is revealing an explanation of the human mind that concludes that moral responsibility and free will are illusions created by our brains. Instead the authors argue that the problem is the assumption that a physicalist/materialistic model of the mind must also be reductionist (a viewpoint that all causes are bottom-up). In this podcast I discuss their arguments against causal reductionism and for a dynamic systems model. We also discuss why we need to avoid brain-body dualism and recognize that our mind is more than just what our brain does. The key to preserving our intuitive sense of our selves as free agents capable of reason, moral responsibility, and free will is that the dynamic systems approach allows top-down causation, without resorting to any supernatural causes or breaking any of the know laws of the physical universe. This is a complex topic, but I present a concise overview of the book’s key ideas.